Results 61 to 70 of about 3,968,782 (301)
Towards Unifying Logical Entailment and Statistical Estimation [PDF]
arXiv, 2022 This paper gives a generative model of the interpretation of formal logic for data-driven logical reasoning. The key idea is to represent the interpretation as likelihood of a formula being true given a model of formal logic. Using the likelihood, Bayes' theorem gives the posterior of the model being the case given the formula. The posterior represents
arxiv
Statistical approach for unpolarized fragmentation functions for the octet baryons
, 2003 A statistical model for the parton distributions in the nucleon has proven its efficiency in the analysis of deep inelastic scattering data, so we propose to extend this approach to the description of unpolarized fragmentation functions for the octet ...
A. D. Martin +59 more
core +2 more sources
FEBS Letters, EarlyView.Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek +15 more
wiley +1 more source
Statistical outliers in random laser emission [PDF]
, 2018 We provide theoretical and experimental evidence of statistical outliers in random laser emission that are not accounted for by the, now established, power-law tailed (L\'evy) distribution.
Cavalieri, Stefano +5 more
core +2 more sources
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Uncovering a generalised gamma distribution: from shape to interpretation [PDF]
arXiv, 2023 In this paper, we introduce the flexible interpretable gamma (FIG) distribution which has been derived by Weibullisation of the body-tail generalised normal distribution. The parameters of the FIG have been verified graphically and mathematically as having interpretable roles in controlling the left-tail, body, and right-tail shape.
arxiv
Reliable and accurate diagnostics from highly multiplexed sequencing assays [PDF]
, 2020 Scalable, inexpensive, and secure testing for SARS-CoV-2 infection is crucial for control of the novel coronavirus pandemic. Recently developed highly multiplexed sequencing assays (HMSAs) that rely on high-throughput sequencing can, in principle, meet ...
Bloom, Joshua S. +8 more
core
Interconnect fatigue design for terrestrial photovoltaic modules [PDF]
, 1982 The results of comprehensive investigation of interconnect fatigue that has led to the definition of useful reliability-design and life-prediction algorithms are presented.
Mon, G. R. +2 more
core +2 more sources
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source