Results 71 to 80 of about 3,968,782 (301)

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Prognostic factors in exacerbated chronic obstructive pulmonary disease

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021
Background: chronic obstructive pulmonary disease has a high prevalence worldwide. It is important to know the mechanisms that have an influence on the high mortality of the exacerbated form of the disease.Objective: to identify the prognostic factors ...
Iraibis Rodríguez-Pérez, Nelsa María Sagaró-del-Campo, Larisa Zamora-Matamoros, Alejandro Martínez-Álvarez   +3 more
doaj  

Interpretable Models for Understanding Immersive Simulations [PDF]

arXiv, 2019
This paper describes methods for comparative evaluation of the interpretability of models of high dimensional time series data inferred by unsupervised machine learning algorithms. The time series data used in this investigation were logs from an immersive simulation like those commonly used in education and healthcare training.
arxiv  

Statistical Workflow for Feature Selection in Human Metabolomics Data. [PDF]

, 2019
High-throughput metabolomics investigations, when conducted in large human cohorts, represent a potentially powerful tool for elucidating the biochemical diversity underlying human health and disease.
Antonelli, Joseph, Cheng, Susan, Claggett, Brian L, Demler, Olga V, Deng, Katherine, Henglin, Mir, Hushcha, Pavel V, Jain, Mohit, Kim, Andy, Kim, Nicole, Lagerborg, Kim A, Mora, Samia, Niiranen, Teemu J, Ovsak, Gavin, Pereira, Alexandre C, Rao, Kevin, Tyagi, Octavia, Watrous, Jeramie D   +17 more
core   +2 more sources

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

A novel statistical analysis and interpretation of flow cytometry data

Journal of Biological Dynamics, 2013
A recently developed class of models incorporating the cyton model of population generation structure into a conservation-based model of intracellular label dynamics is reviewed. Statistical aspects of the data collection process are quantified and incorporated into a parameter estimation scheme. This scheme is then applied to experimental data for PHA-
Banks, H. Thomas, Kapraun, Dustin F., Thompson, W. Clayton, Peligero Cruz, Cristina, 1986-, Argilaguet Marqués, Jordi, 1977-, Meyerhans, Andreas   +5 more
openaire   +4 more sources

Biomass-density data analysis: a comment on Cabaco et al. (2013) [PDF]

, 2015
Appropriate use of mathematics and statistics is fundamental for sound interpretations of ecological results and to prevent inaccurate conclusions. Throughout the article by Cabaco etal.
Arenas, Cabaço, Chu, Chu, Creed, Creed, Dowdy, Jackson, Jolliffe, Manly, Morris, Morris, Morris, Rincón, Sokal, Sousa, Steen, Turner, Underwood, Vieira, Vieira   +20 more
core   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Application of Statistical Tools for Data Analysis and Interpretation in Rice Plant Pathology

Rice Science, 2018
There has been a significant advancement in the application of statistical tools in plant pathology during the past four decades. These tools include multivariate analysis of disease dynamics involving principal component analysis, cluster analysis ...
Parsuram Nayak, Arup Kumar Mukherjee, Elssa Pandit, Sharat Kumar Pradhan   +3 more
doaj   +1 more source

goCluster integrates statistical analysis and functional interpretation of microarray expression data [PDF]

, 2017
Motivation: Several tools that facilitate the interpretation of transcriptional profiles using gene annotation data are available but most of them combine a particular statistical analysis strategy with functional information.
Chalmel, Frédéric, Primig, Michael, Wrobel, Gunnar   +2 more
core