Results 171 to 180 of about 1,251,881 (338)

Chromosome 21 non-disjunction and Down syndrome birth in an Indian cohort: analysis of incidence and aetiology from family linkage data [PDF]

, 2010
Sujoy Ghosh, Pranami Bhaumik, Priyanka Ghosh, Subrata Kumar Dey   +3 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

International Health Data Linkage Network

Healthcare Policy | Politiques de Santé, 2011
Merran, Smith, James, Semmens, Diana, Rosman, Jane, Ford, Catherine, Storey, C D'Arcy J, Holman, Emma, Fuller, Victoria, Gray   +7 more
openaire   +3 more sources

The impact of risk‐reducing hysterectomy and bilateral salpingo‐oophorectomy on survival in patients with a history of breast cancer—A population‐based data linkage study [PDF]

, 2013
Andreas Obermair, Danny R. Youlden, Peter D. Baade, Monika Janda   +3 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Optimizing data linkage for maximizing the potential of Luxembourg's national cancer registry: a comprehensive scoping review. [PDF]

Front Oncol
Lima B, Hasan F, Kannan P, Schnell M, Mafra A, Couffignal S, Backes C.   +6 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Healthcare utilization for eating disorders in Australia: 10 years of health data linkage. [PDF]

Aust N Z J Psychiatry
Dann KM, Schneuer FJ, Miskovic-Wheatley J, Cunich M, Ahmed M, Sidari M, Sara G, Griffiths KR, Russell J, Touyz S, Madden S, Diffey C, Withington T, Roberton M, Ward W, Hannigan A, Nassar N, Maguire S.   +17 more
europepmc   +1 more source

Maternal Cannabis Use Disorder and Risk of Adverse Neonatal Outcomes: A Data Linkage Study

Abay Woday Tadesse, Kim Betts, Berihun Assefa Dachew, Getinet Ayano, Rosa Alati   +4 more
openalex   +1 more source

Frequent Attendance to the Emergency Department after Release from Prison: a Prospective Data Linkage Study [PDF]

, 2019
Amanda Butler, Alexander Love, Jesse T Young, Stuart A. Kinner   +3 more
openalex   +1 more source