Results 231 to 240 of about 25,746,555 (330)

Coagulation and Transfusion Informatics in Chronic Liver Disease: A Data Linkage Study of Emergency Department Presentations. [PDF]

EJHaem
Latona A, Smith E, Grant J, Mitra B.
europepmc   +1 more source

omicsPrint: detection of data linkage errors in multiple omics studies

Bioinform., 2018
M. Iterson, D. Cats, P. Hop, B. Consortium, B. Heijmans   +4 more
semanticscholar   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Health inequalities and trends in heart failure diagnosis in primary care in England, 2000-21: a national retrospective cohort data-linkage study. [PDF]

Lancet Prim Care
Lawson CA, Ali MR, McCann GP, Squire I, Zaccardi F, Rashid M, Barber K, Alaei Kalajahi R, Miller CA, Williams R, Clark AL, Petrie MC, Taylor CJ, Friday JM, Conrad N, Cleland JGF, Khunti K.   +16 more
europepmc   +1 more source

Association of birth defects with the mode of assisted reproductive technology in a Chinese data-linkage cohort.

Fertility and Sterility, 2018
Huiting Yu, Qing Yang, Xiao-Xi Sun, Guo-wu Chen, N. Qian, R. Cai, Hanbing Guo, Chunfang Wang   +7 more
semanticscholar   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Long-term adherence to glucose-lowering medications in adults with diabetes: A data linkage study. [PDF]

Diabetes Obes Metab
Lee CMY, Gibson AA, Nassar N, Colagiuri S.   +3 more
europepmc   +1 more source

Estimation of linkage with censored data [PDF]

Heredity, 1964
openaire   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source