Results 81 to 90 of about 891,248 (273)
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Scientific ReportsLimited information is available on the cardiovascular health (CVH) index and risk of high-normal blood pressure (HNBP) in elderly people. Randomized cluster sampling, multivariate logistic regression, and mediating effects analysis were used in this ...
Yongcheng Ren +13 more
doaj +1 more source
Data Management For Training Large Language Models: A Survey [PDF]
arXiv, 2023 Data plays a fundamental role in training Large Language Models (LLMs). Efficient data management, particularly in formulating a well-suited training dataset, is significant for enhancing model performance and improving training efficiency during pretraining and supervised fine-tuning stages.
arxiv
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Cost Efficiency for Economical Mobile Data Traffic Management from Users' Perspective [PDF]
arXiv, 2016 Explosive demand for wireless internet services has posed critical challenges for wireless network due to its limited capacity. To tackle this hurdle, wireless Internet service providers (WISPs) take the smart data pricing to manage data traffic loads.
arxiv
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
In-silico evaluation of the T-cell based immune response against SARS-CoV-2 omicron variants
Scientific ReportsDuring of COVID-19 pandemic, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has continuously evolved, resulting in the emergence of several new variants of concerns (VOCs) with numerous mutations. These VOCs dominate in various regions due
Shivangi Sharma, Diya Roy, Sarah Cherian
doaj +1 more source
BUDAMAF: Data Management in Cloud Federations [PDF]
arXiv, 2018 Data management has always been a multi-domain problem even in the simplest cases. It involves, quality of service, security, resource management, cost management, incident identification, disaster avoidance and/or recovery, as well as many other concerns. In our case, this situation gets ever more complicated because of the divergent nature of a cloud
arxiv
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source