Results 111 to 120 of about 22,484,217 (350)

Development and evaluation of multiepitope fusion proteins for serological diagnosis of animal brucellosis

Microbiology Spectrum
Brucellosis, a zoonotic disease caused by Brucella spp., leads to severe reproductive issues in livestock and economic losses. Current serological diagnostics using lipopolysaccharide (LPS) antigens often exhibit cross-reactivity, reducing diagnostic ...
Liping Guo, Qichuan Pei, Shiqi Zhao, Xinru Qi, Yixiao Chen, Peifei Yang, Yangguang Du, Mingjun Sun, Dehui Yin, Tiansong Zhan   +9 more
doaj   +1 more source

Implementasi Data Mining dengan Metode Naive Bayes Untuk Memprediksi Penerimaan Siswa Baru di MTS NU Islamiyah Asembagus

, 2023
Firman Santoso, Sunardi Sunardi, Hifni Zainul Lukman   +2 more
openalex   +2 more sources

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Data mining

International Journal of Scientific Research and Management (IJSRM)
Data Mining Data mining is about finding patterns in the data [1]. In this paper, I put forward an important insight about similarity in branches of computer science and data mining. All branches of computer science could be termed as a procedure to carry out data mining. In this paper, I detail that. The computer works by finding patterns in the input
openaire   +2 more sources

Retracted: Prevention Methods of Fitness and Bodybuilding Exercise Injury Based on Data Mining [PDF]

, 2022
Computational and Mathematical Methods in Medicine
openalex   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

A Knowledge Graph-Enhanced Hidden Markov Model for Personalized Travel Routing: Integrating Spatial and Semantic Data in Urban Environments

Smart Cities
Personalized urban services are becoming increasingly significant in smart city systems. This shift from intelligent transportation to smart cities broadens the scope of personalized services, encompassing not just travel but a wide range of urban ...
Zhixuan Zeng, Jianxin Qin, Tao Wu
doaj   +1 more source

Autopolyploidization‐Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa

Advanced Science, EarlyView.
This study demonstrates that monoploid, diploid, and autotetraploid Brassica rapa lines derived from the same genome exhibit distinct leaf morphology. Ploidy changes remodel chromatin accessibility and histone modifications to regulate gene expression, while key transcription factors BrGRF13 and BrARF11 control leaf size and polarity, driving ...
Haoyuan Dong, Yanhong Liu, Yuanming Liu, Shuxin Xuan, Huanhuan Chen, Lai Wei, Guibao Zhang, Hongcui Pei, Zilong Dai, Yanhua Wang, Jinzhu Qiao, Shuangxia Luo, Xueping Chen, Yiguo Hong, Jianjun Zhao, Shuxing Shen, Zefu Lu, Aixia Gu   +17 more
wiley   +1 more source