Results 111 to 120 of about 1,594,032 (285)

A data mining framework for optimal product selection in retail supermarket data [PDF]

open access: bronze, 2000
Tom Brijs   +4 more
openalex   +1 more source

Capsaicin Alleviates Autophagy‐Lysosomal Dysfunction via PPARA‐Mediated V‐ATPase Subunit ATP6V0E1 Signaling in 3xTg‐AD Mice

open access: yesAdvanced Science, EarlyView.
Capsaicin enhances lipid metabolism, reduces lipid deposition, and alleviates AD‐related pathologies. Capsaicin activates PPARA, promoting the expression of PPAR signaling pathway‐related genes and accelerating lipid metabolism. Capsaicin upregulates ATP6V0E1‐V‐ATPase‐mediated lysosomal acidification, enhancing lipid droplet clearance. PPARA is the key
Haitao Yu   +12 more
wiley   +1 more source

Scalable data mining with model constraints [PDF]

open access: bronze, 2000
Minos Garofalakis, Rajeev Rastogi
openalex   +1 more source

Sparse Nanocrystals Enable Ultra‐Low Coercivity and Remarkable Mechanical Robustness in High‐Entropy Amorphous Alloy

open access: yesAdvanced Science, EarlyView.
An order modulation strategy is introduced to overcome trade‐off between mechanical and magnetic properties by constructing an amorphous‐nanocrystalline transitional structure in a ferromagnetic HEA system. This enable the resultant alloys to combine an ultra‐low coercivity of 0.3 A m−1 with a remarkable mechanical toughness, thereby achieving a ...
Lichen Liu   +8 more
wiley   +1 more source

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo   +7 more
wiley   +1 more source

DeepSecMS Advances DIA‐Based Selenoproteome Profiling Through Cys‐to‐Sec Proxy Training

open access: yesAdvanced Science, EarlyView.
DeepSecMS, a deep learning platform leveraging a Cys‐to‐Sec proxy training strategy, enhances the identification of known selenoproteins and holds promise for discovering novel candidates. This proxy approach overcomes limitations associated with the rarity of known selenoproteins and demonstrates broad applicability in studying other rare protein ...
Chenfang Si   +5 more
wiley   +1 more source

Transformation of a Silicate Material for Carbon Negative Magnesia‐Based Cement via Electrochemistry

open access: yesAdvanced Science, EarlyView.
The transformation of a magnesium trisilicate material via water electrolysis into precursor phases necessary for magnesium‐based M‐S‐H cement is explored. The dissolution of the material mediated electrochemically is monitored, and the analysis of the resulting phases indicate their suitability as effective precursors for M‐S‐H cement.
Anthony R. Ramuglia   +11 more
wiley   +1 more source

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