Results 141 to 150 of about 25,216,828 (261)
Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer
Advanced Science, EarlyView.In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen +10 more
wiley +1 more source
China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications
Advanced Science, EarlyView.China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu +3 more
wiley +1 more source
RESEARCH ISSUES CONCERNING ALGORITHMS USED FOR OPTIMIZING THE DATA MINING PROCESS [PDF]
In this paper, we depict some of the most widely used data mining algorithms that have an overwhelming utility and influence in the research community. A data mining algorithm can be regarded as a tool that creates a data mining model.
Alexandru Pîrjan, Ion Lungu
core
Advanced Science, EarlyView.This study identifies MZF1 as a core regulator of colon cancer via SnoN‐mediated TGF‐β suppression, proposes 10Panx Acetate as a targeted inhibitor, and validates MZF1/SnoN as prognostic markers for aggressive disease. ABSTRACT Colon cancer progression is associated with transcriptional and signaling abnormalities.
Siqi Sheng +9 more
wiley +1 more source
APPLICATION OF NEURAL NETWORKS IN PREDICTIVE DATA MINING [PDF]
Neural Networks represent a meaningfully different approach to using computers in the workplace. A neural network is used to learn patterns and relationships in data. The data may be the results of a market research effort, or the results of a production
Saratha Sathasivam
core
Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes
Advanced Science, EarlyView.In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley +1 more source
Algorithms for Extracting Frequent Episodes in the Process of Temporal Data Mining [PDF]
An important aspect in the data mining process is the discovery of patterns having a great influence on the studied problem. The purpose of this paper is to study the frequent episodes data mining through the use of parallel pattern discovery algorithms.
Alexandru PIRJAN
core
Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy
Advanced Science, EarlyView.Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song +7 more
wiley +1 more source
WEB MINING IN E-COMMERCE [PDF]
Recently, the web is becoming an important part of people’s life. The web is a very good place to run successful businesses. Selling products or services online plays an important role in the success of businesses that have a physical presence, like a ...
Istrate Mihai
core
Advanced Science, EarlyView.We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang +19 more
wiley +1 more source