Results 161 to 170 of about 19,155,994 (294)

Unraveling the Autism Spectrum Heterogeneity: Insights From ABIDE I Database Using Data/Model-Driven Permutation Testing Approaches. [PDF]

Brain Behav
Alcaide FJ, Illan IA, Ramírez J, Gorriz JM.   +3 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

FDBRP: A Data-Model Co-Optimization Framework Towards Higher-Accuracy Bearing RUL Prediction. [PDF]

Sensors (Basel)
Lin M, Ye Q, Na S, Qin D, Gao X, Liu Q.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Pain when it "counts": hurdle analysis of clinical pain ratings improves data model performance. [PDF]

Pain Rep
Hogans BB, Siaton BC, Sorkin JD.
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Models, data models, and big data

Leticia Castillo Brache, Alisa Bokulich
openaire   +1 more source

Exploring common data model coverage of nursing flowsheet data: a pilot study using SNOMED CT and LOINC mapping. [PDF]

JAMIA Open
Austin R, Britt Lalich M, Stewart K, Zarbano J, Byrne M, Pinto MD, Umberfield EE.   +6 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Establishing standards: harmonising coding principles for a minimal cancer dataset in the OMOP Common Data Model. [PDF]

ESMO Real World Data Digit Oncol
Ajmal A, Bouissou O, Brash J, Cheeseman S, Banduge PG, Gomes AL, Revie L, Ross E, Theophanous S, Thonnard J, Van Maanen A, Vengadeswaran A, Wolf A, Fernandez XM.   +13 more
europepmc   +1 more source