Results 181 to 190 of about 39,466,651 (301)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Enhancing multimodal inpatient fall prediction via nursing statement integration within the OMOP common data model. [PDF]

Sci Rep
Hong H, Kim S, Ryu B.
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

An OMOP Common Data Model pipeline for electrocardiography dataset integration by standardizing signal metadata and heart rate variability features. [PDF]

Front Bioinform
Reali P, Tibollo V, Riboni G, Plebani P, Tanca L, Signorini MG.   +5 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Changes in postoperative pneumonia incidence after the pandemic: a retrospective observational study using a common data model. [PDF]

Anesth Pain Med (Seoul)
Kim DH, Seo H, Lee Y, Kim IS, Kim M, Lim YH, Kim JE, Choi SI, Song S, Lim BG, Park M, Koo BS, Yoo JH, Kim DH, Choi JB, Kim H, Lee C, Yoo SH, Yu HK, Noh C, Lee DK, Kwak SG.   +21 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

CohortCharacteristics: an R package for population characterisation in observational studies using the OMOP common data model. [PDF]

Eur J Epidemiol
Du M, Prats-Uribe A, Mercadé-Besora N, Lopez-Guell K, Guo Y, Alcalde-Herraiz M, Chen X, Delmestri A, Man WY, Duarte-Salles T, Palomar A, Giuliodori A, Brađašević E, Jezidžić A, Bräuner E, Bruun S, Verhamme K, Mosseveld M, Brash JT, Vojinovic D, Kaczmarczyk I, Mendez A, Rijnbeek P, Prieto-Alhambra D, Burn E, Català M.   +25 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Models, data models, and big data

Leticia Castillo Brache, Alisa Bokulich
openaire   +1 more source