Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Quantile regression for static panel data models with time-invariant regressors. [PDF]
Tao L, Tai L, Tian M.
europepmc +1 more source
Atmospheric transmission models for FORCAST (39deg O3): altitude 43kft, zenith 35deg
This dataset contains atmospheric transmission models calculated by a modified version of ATRAN (atran_sdc). They are to be used as the default models for FORCAST data reduction with SOFIA Redux.
SOFIA Data Center
core +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Integration Patterns Development for Enterprise Software Systems
The work concerns the pattern building for heterogeneous enterprise information systems (IS). Quite a heavy data burden has been accumulated by the enterprises, and it tends to increase further.
S. V. Zykov
doaj
Methods Used in the Development of Common Data Models for Health Data: Scoping Review. [PDF]
Ahmadi N +6 more
europepmc +1 more source
Atmospheric transmission models for FORCAST (39deg O3): altitude 43kft, zenith 70deg
This dataset contains atmospheric transmission models calculated by a modified version of ATRAN (atran_sdc). They are to be used as the default models for FORCAST data reduction with SOFIA Redux.
SOFIA Data Center
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The future of heart transplant data science requires common data models. [PDF]
Chhikara K, Parker WF.
europepmc +1 more source
Editorial: Open-access data, models and resources in neuroscience research. [PDF]
Zaletel I, Nowakowski RS, Ness TV.
europepmc +1 more source

