Results 171 to 180 of about 24,365,275 (295)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Genetic data normalization for genomic medicine: a Fast Healthcare Interoperability Resources Genomics reference implementation. [PDF]

J Am Med Inform Assoc
Dolin RH, Todor NM, Shalaby J, Arsalan H, Shah E, Basravi N, Husami A, Rampersad A, Heale BSE, Chamala S.   +9 more
europepmc   +1 more source

The disguised pandemic: the importance of data normalization in COVID-19 web mapping. [PDF]

Public Health, 2020
Adams A, Li W, Zhang C, Chen X.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Data normalization of plasma miRNA profiling from patients with COVID-19. [PDF]

Sci Rep
Siguemoto JT, Motta Neri C, de Godoy Torso N, de Souza Nicoletti A, Berlofa Visacri M, Regina da Silva Correa da Ronda C, Perroud MW, Oliveira Reis L, Dos Santos LA, Durán N, Fávaro WJ, de Carvalho Pincinato E, Moriel P.   +12 more
europepmc   +1 more source

CORAZON: a web server for data normalization and unsupervised clustering based on expression profiles. [PDF]

BMC Res Notes, 2020
Ramos TAR, Maracaja-Coutinho V, Ortega JM, do Rêgo TG.   +3 more
europepmc   +1 more source

From gene-expressions to pathways [PDF]

Rapid advancements in experimental techniques have benefited molecular biology in many ways. The experiments once considered impossible due to the lack of resources can now be performed with relative ease in an acceptable time-span; monitoring ...
Krishna, Ritesh V.
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Multivariate Strategy for Understanding Soil Features from Rare-Earth Element Profiles: A Focus on Data Normalization. [PDF]

ACS Meas Sci Au
Barbera M, Gariglio S, Malegori C, Oliveri P, Saiano F, Scalenghe R, Piazzese D.   +6 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source