Results 121 to 130 of about 2,002,690 (314)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Utilizing Hybrid P4 Solutions to Enhance 5G gNB with Data Plane Programmability

open access: yes
The typical approach to data plane programming involves deploying a single P4 program to a single target. However, different targets have different capabilities, functionalities, and support for various programming languages apart from P4.
Laki, Sandor,   +11 more
core   +1 more source

Stateful Data Plane Abstractions for Software-Defined Networks and Their Applications [PDF]

open access: yes, 2017
RÉSUMÉ: ABSTRACT Software-Defined Networking (SDN) enables programmability in the network. Unfortunately, current SDN limits programmability only to the control plane.
Cascone, Carmelo
core  

Resilient Network Architecture with eBPF-based Programmability and Centralised Orchestration [PDF]

open access: yes
—In traditional computer network architectures, scalability can be slow and costly, and lack inherent support for resilience increasingly required by modern use-cases applications.
Holik, Filip   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Design and Implementation of Reliable SDN Control Plane over Data Plane Network

open access: yes, 2015
Software-Dened Networking (SDN) enables dynamic and adaptable network through directly programmability from services and applications. OpenFlow, which is reference architecture of SDN, decouples the network management plane from the data transfer plane ...
橋本 直樹
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Programmable control plane for mission critical wireless networks

open access: yes, 2017
The control plane is an essential element to manage the data plane communications in wired and wireless networks. In a traditional network architecture, the control plane is embedded in the hardware and it lacks programmability.
Brian Jalaian   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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