Results 131 to 140 of about 8,948 (289)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
An Intelligent and Programmable Data Plane for QoS-Aware Packet Processing
IEEE Transactions on Machine Learning in Communications and NetworkingOne of the main features of data plane programmability is that it allows the easy deployment of a programmable network traffic management framework. One can build an early-stage Internet traffic classifier to facilitate effective Quality of Service (QoS)
Muhammad Saqib +3 more
doaj +1 more source
Impact of SDN Controllers Deployment on Network Availability
, 2016 Software-defined networking (SDN) promises to improve the programmability and flexibility of networks, but it may bring also new challenges that need to be explored.
Gonzalez, Andres J. +4 more
core
The Offloading Dilemma: Exploring the Boundaries of Programmable Data Planes
2025 IEEE 11th International Conference on Network Softwarization (NetSoft)In-Network Computing (INC) is transforming how we design and evaluate modern networks by enabling programmable data planes to execute computational tasks at line rate. However, deciding which functions to offload, to which device and using which strategy is not a trivial task.
Vogt, Francisco +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
IEEE AccessSoftware-Defined Networking (SDN) is a network architecture that offers enhanced flexibility, programmability, and more efficient traffic load management by decoupling the control plane from the data plane.
Kai Yuan Tan +2 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source