Results 101 to 110 of about 584,673 (292)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Cryptographic Accumulator-Based Scheme for Critical Data Integrity Verification in Cloud Storage

open access: yesIEEE Access, 2019
Public cloud storage is a fundamental cloud computing service. Currently, most owners of large data outsource their data to cloud storage services-even high-profile owners such as governments.
Walid I. Khedr   +2 more
doaj   +1 more source

Discretion, Due Process, and the Prison Discipline Committee [PDF]

open access: yes, 1985
A revised version of this paper was published as: Schafer, N.E. (1986). "Discretion, Due Process and the Prison Discipline Committee." Criminal Justice Review 11(2): 37–46 (Fall 1986).
Schafer, N. E.
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Global Adoption of Convenience Foods [PDF]

open access: yes
Trends in the types of foods Americans purchase are evident just by looking around the grocery store. Foods stuffs requiring extensive preparation are being replaced by convenience products that require little time, energy, or preparation. Food companies
Sheely, Megan
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Knowledge and possession of take-home naloxone kits among street-involved youth in a Canadian setting: a cohort study

open access: yesHarm Reduction Journal, 2017
Background The distribution of take-home naloxone (THN) kits has been an important strategy in reducing overdose fatalities among people who use drugs. However, little is known about the use of THN among youth who are street-involved.
Julia Goldman-Hasbun   +5 more
doaj   +1 more source

Justice Reinvestment in Oklahoma: Analysis and Policy Framework [PDF]

open access: yes, 2012
Summarizes findings from analyses of criminal justice, mental health, and substance abuse data and policy options for justice reinvestment, a data-driven strategy to contain corrections spending and reinvest part of the savings in improving public ...

core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Provable data possession scheme based on public verification and private verification

open access: yesTongxin xuebao, 2019
More and more users choose to transfer their applications and data into the cloud.Data security is a key issue for cloud storage systems.To ensure the integrity and validity of the data stored in the cloud,provable data possession (PDP) scheme is ...
Junfeng TIAN, Mengjia CHAI, Liuling QI
doaj   +2 more sources

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