Results 201 to 210 of about 334,461 (264)

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Performance and energy consumption optimization of ternary optical computers based on the M/G/1 queuing model. [PDF]

Sci Rep
Wenqiang S, Weiwen L, Heqiang Z, Meng L, Sulan Z, Xianchao W.   +5 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

EQISP: efficient quantized image signal processing with multi-scale pyramid fusion for resource constrained embodied perception. [PDF]

Front Neurorobot
Yang T, Guo L, Li J, Qin Q, Liu B, Zhang Q.   +5 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

ECLARE: efficient cross-planar learning for anisotropic resolution enhancement. [PDF]

J Med Imaging (Bellingham)
Remedios SW, Wei S, Han S, Zhang J, Carass A, Schilling KG, Pham DL, Prince JL, Dewey BE.   +8 more
europepmc   +1 more source

TCRBinder: Unified pre-trained language model with paired-chain synergy for predicting T-cell receptor binding specificity. [PDF]

PLoS Comput Biol
Dong W, Yang Q, Xu L, Li X, Wang K, Dong S, Luo G, Zhang X, Yang T, Gao X, Wang G.   +10 more
europepmc   +1 more source