Results 121 to 130 of about 22,562,908 (328)

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

open access: yesMolecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen   +6 more
wiley   +1 more source

Location publishing technology based on differential privacy-preserving for big data services

open access: yesTongxin xuebao, 2016
Aiming at dealing with prospect knowledge and complex combinatorial attack,a new location big data publishing mechanism under differential privacy technology was given.And innovative usability evaluation feedback mechanism was designed.It gave ...
Lin ZHANG, Yan LIU, Ru-chuan WANG
doaj  

The academic, economic and societal impacts of Open Access: an evidence-based review [version 2; referees: 4 approved, 1 approved with reservations]

open access: yesF1000Research, 2016
Ongoing debates surrounding Open Access to the scholarly literature are multifaceted and complicated by disparate and often polarised viewpoints from engaged stakeholders.
Jonathan P. Tennant   +5 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Differential privacy protection technology and its application in big data environment

open access: yesTongxin xuebao, 2019
The privacy protection in big data is a research hotspot in the field of cyberspace security.As a strict and provable definition of privacy protection,studying application status of differential privacy protection in big data environment can provide ...
Yu FU, Yihan YU, Xiaoping WU
doaj  

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

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