Results 81 to 90 of about 4,056,714 (290)

ICT Use, Environmental Quality Perception and Farmers’ Participation in Domestic Waste Separation: Micro-Survey Data from China [PDF]

, 2023
Fan Chen, Jianyi Jiao, Zhongan Wu, Can Zhang   +3 more
openalex   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Strengthening team building and capacity development for data quality: the case of hiv program in delta state, nigeria

, 2023
Tommy Umukoro, Paul Marcus, Uparegh Imoter, Okpanachi Oko, Olanrewaju Olayiwola   +4 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Calculating the similarity between prescriptions to find their new indications based on graph neural network

Chinese Medicine
Background Drug repositioning has the potential to reduce costs and accelerate the rate of drug development, with highly promising applications. Currently, the development of artificial intelligence has provided the field with fast and efficient ...
Xingxing Han, Xiaoxia Xie, Ranran Zhao, Yu Li, Pengzhen Ma, Huan Li, Fengming Chen, Yufeng Zhao, Zhishu Tang   +8 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Regulatory landscape with U.S. patient requirements and Clinical Trial Diversity expectations

Contemporary Clinical Trials Communications
The Food and Drug Administration (FDA) has an expectation that products filed for marketing authorization have to include data that are representative of the US patient population.
Elizabeth George, Alicia Baker McDowell, Melissa Vozza, Talley Mitchell, Ben Quartley, Cassandra S. Kennedy, Bill Hanlon   +6 more
doaj   +1 more source

The impacts of poor data quality on business performance

, 2023
Trinh Hoang Hong Hue, Thien-Vu Tran
openalex   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Reflection on Quality Assurance of Government Statistic Data [PDF]

, 2017
Shunqi Hu
openalex   +1 more source