Results 81 to 90 of about 12,375,470 (271)

Measurements of sulphur dioxide in rural air: data quality issues [PDF]

, 2011
Discrepancies between long-term average SO2 concentrations measured by UV-Fluorescence monitors in the AURN and DELTA denuders from AGA-Net are caused by inadequate performance of UV-F monitors at low concentrations.
Cape, J.N.
core  

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Prevalence of overweight/obesity and its association with fast food consumption among adolescents in Southern Ethiopia, 2022: a community-based cross-sectional study

Frontiers in Nutrition
Overweight and obesity are body mass index (BMI) for age Z-score > +1SD and > +2SD, respectively. Despite its largest contribution to overweight/obesity, there is little attention in our country about fast-food consumption.
Chernet Elias, Awoke Abraham, Chernet Asrat, Tagese Yakob, Daniel Girma   +4 more
doaj   +1 more source

Distribution- and anchor-based methods to determine the minimally important difference on patient-reported outcome questionnaires in oncology: a structured review

Health and Quality of Life Outcomes, 2018
Background Interpretation of differences or changes in patient-reported outcome scores should not only consider statistical significance, but also clinical relevance.
Ahmad Ousmen, Célia Touraine, Nina Deliu, Francesco Cottone, Franck Bonnetain, Fabio Efficace, Anne Brédart, Caroline Mollevi, Amélie Anota   +8 more
doaj   +1 more source

Measuring and Managing Answer Quality for Online Data-Intensive Services

, 2015
Online data-intensive services parallelize query execution across distributed software components. Interactive response time is a priority, so online query executions return answers without waiting for slow running components to finish.
Elnikety, Sameh, He, Yuxiong, Kelley, Jaimie, Morris, Nathaniel, Stewart, Christopher, Tiwari, Devesh   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Discontinuation of Heart Failure Pharmacotherapy in Older Adults With Frailty

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Guideline‐directed medical therapy (GDMT) improves outcomes in heart failure irrespective of frailty status. Nevertheless, the magnitude of frailty‐associated discontinuation of GDMT remains insufficiently studied.
Ryo Nakamaru, Shiori Nishimura, Hiraku Kumamaru, Kyohei Daigo, Kayo M. Walsh, Shun Kohsaka   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source