Results 91 to 100 of about 4,521,941 (297)

Robust estimation of dimension reduction space [PDF]

Most dimension reduction methods based on nonparametric smoothing are highly sensitive to outliers and to data coming from heavy-tailed distributions. We show that the recently proposed methods by Xia et al.
Wolfgang Härdle, Pavel Cizek
core   +3 more sources

Ketamine induces multiple individually distinct whole-brain functional connectivity signatures

eLife
Background: Ketamine has emerged as one of the most promising therapies for treatment-resistant depression. However, inter-individual variability in response to ketamine is still not well understood and it is unclear how ketamine’s molecular mechanisms ...
Flora Moujaes, Jie Lisa Ji, Masih Rahmati, Joshua B Burt, Charles Schleifer, Brendan D Adkinson, Aleksandar Savic, Nicole Santamauro, Zailyn Tamayo, Caroline Diehl, Antonija Kolobaric, Morgan Flynn, Nathalie Rieser, Clara Fonteneau, Terry Camarro, Junqian Xu, Youngsun Cho, Grega Repovs, Sarah K Fineberg, Peter T Morgan, Erich Seifritz, Franz X Vollenweider, John H Krystal, John D Murray, Katrin H Preller, Alan Anticevic   +25 more
doaj   +1 more source

Replication data for : Autoencoder-Based Dimensionality Reduction of Turbulent Channel Flow Under Spanwise Wall Oscillations [PDF]

The present dataset contains 2D slices of a turbulent channel flow under spanwise wall oscillations, obtained from simulations with varying actuation amplitudes.
Cordier, Laurent, Flageul, Cédric, Agostini, Lionel, Fisk, Thomas, Guerin, Lou   +4 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Identification and data-driven model reduction of state-space representations of lossless and dissipative systems from noise-free data [PDF]

, 2011
We illustrate procedures to identify a state-space representation of a lossless- or dissipative system from a given noise-free trajectory; important special cases are passive- and bounded-real systems.
Trentelman, Harry, Rapisarda, P., Paolo Rapisarda, Trentelman, H.L., Trentelman, H.L.,, P. Rapisarda, Rapisarda, P.,, Harry L. Trentelman, H.L. Trentelman, Rapisarda, Paolo   +9 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Block sparsity-based joint compressed sensing recovery of multi-channel ECG signals

Healthcare Technology Letters, 2017
In recent years, compressed sensing (CS) has emerged as an effective alternative to conventional wavelet based data compression techniques. This is due to its simple and energy-efficient data reduction procedure, which makes it suitable for resource ...
Anurag Singh, Samarendra Dandapat
doaj   +1 more source

Oxidation and reduction data of subphthalocyanines

Data in Brief, 2020
The data presented in this paper are related to the research article entitled "Electrochemical behaviour of chloro- and hydroxy-subphthalocyanines" [1]. This paper presents detailed oxidation and reduction potential data, obtained from cyclic voltammograms of three subphthalocyanines (SubPcs), in both dichloromethane (DCM) and dichloroethane (DCE) as ...
Pieter J. Swarts, Jeanet Conradie
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source