Results 101 to 110 of about 4,521,941 (297)

MuscleX: data analysis software for fiber diffraction patterns from muscle

Journal of Synchrotron Radiation
MuscleX is an integrated, open-source computer software suite for data reduction of X-ray fiber diffraction patterns from striated muscle and other fibrous systems. It is written in Python and runs on Linux, Microsoft Windows or macOS.
Jiranun Jiratrakanvong, Jinjian Shao, Jiaqi Li, Miguel Menendez Alvarez, Xintian Li, Prajwal Das, Grant Nikseresht, Nikhil Miskin, Ran Huo, Jules Nabon, Tristan Leduc, Eric Zhang, Weikang Ma, Gady Agam, Thomas C. Irving   +14 more
doaj   +1 more source

System- and Data-Driven Methods and Algorithms Model order reduction ;, v. 1./ edited by Peter Benner [and others]. [PDF]

, 2021
Includes bibliographical references and index."An increasing complexity of models used to predict real-world systems leads to the need for algorithms to replace complex models with far simpler ones, while preserving the accuracy of the predictions.
Benner Peter
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

High-Contrast Imaging: Hide and Seek with Exoplanets

Galaxies
So far, most of the about 5700 exoplanets have been discovered mainly with radial velocity and transit methods. These techniques are sensitive to planets in close orbits, not being able to probearge star–planet separations.
Riccardo Claudi, Dino Mesa
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Harm reduction among injecting drug users - evidence of effectiveness [PDF]

, 2010
This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Rhodes, T., Kerr, Thomas, Palmateer, N., Goldberg, David J., Hedrich, Dagmar, Palmateer, Norah, Fry, Craig L, Goldberg, David, Palmateer, Norah; id_orcid, Rhodes, Tim, Goldberg, D.J., Stöver, H., Hickman, Matthew, Hutchinson, Sharon, Hall, Wayne, Hickman, M., Brentari, C., Kimber, J., Kimber, Jo, Fischer, Benedikt, Hutchinson, S.J., Stevens, Alex, Dubois-Arber, Françoise, Hutchinson, Sharon J.; id_orcid   +23 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Replication Data for: Charge transfer enhancement at the CZTS photocathode interface using ITO for efficient solar water reduction [PDF]

Replication Data for: Charge transfer enhancement at the CZTS photocathode interface using ITO for efficient solar water ...
Lie, Stener, Wong, Lydia Helena, Zhang, Shuo, Tay, Ying Fan, Zhang, Mengyuan, Chiam, Sing Yang   +5 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source