Results 121 to 130 of about 30,090,669 (294)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
On data reduction for Boolean matrix factorization
In the associated paper, "On data reduction for Boolean matrix factorization,'' we examine existing work on data reduction for the problem of factorization of Boolean data and propose a new data-reduction method. This supplement to the paper contains two
Juracka, Jakub
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Effects of LiDAR Data Reduction and Breaklines on the Accuracy of Digital Elevation Model
This paper explores the effects of LiDAR data reduction on the accuracies of produced TINs and gridded DEMs. It examined to what extent a set of LiDAR (light detection and ranging) data can be reduced without sacrificing the accuracy of produced terrain ...
Liu, Xiaoye +3 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Current Questions on Bureaucracy Reduction
Questions on bureaucracy reduction. Topics: Connotation of the term bureaucracy reduction; importance of the topic bureaucracy reduction; progress of the federal government in the reduction of bureaucracy.
Presse- und Informationsamt der Bundesregierung, Berlin
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Parks and Gardens Data Service
Parks and Gardens UK is the leading on-line resource for historic parks and gardens providing freely accessible, accurate and inspiring information on UK parks, gardens and designed landscapes and all activities concerned with their promotion ...
Parks and Gardens Data Service
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

