Results 121 to 130 of about 25,840,748 (312)

Weighted voting for replicated data [PDF]

open access: yesProceedings of the seventh symposium on Operating systems principles - SOSP '79, 1979
In a new algorithm for maintaining replicated data, every copy of a replicated file is assigned some number of votes. Every transaction collects a read quorum of rvotes to read a file, and a write quorum of wvotes to write a file, such that r+w is greater than the total number of votes assigned to the file.
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A Fault-Tolerant Mobile Computing Model Based On Scalable Replica

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence, 2014
The most frequent challenge faced by mobile user is stay connected with online data, while disconnected or poorly connected store the replica of critical data.
Meenakshi Sati   +7 more
doaj   +1 more source

Mediating effect of pubertal stages on the family environment and neurodevelopment: An open-data replication and multiverse analysis of an ABCD Study<sup>®</sup>. [PDF]

open access: yesNeuroimage Rep, 2022
Demidenko MI   +9 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Replication Data for: Strangers, friends, and lovers show specific physiological synchronies in different emotional contexts

open access: yes, 2020
This repository contains replication data for the study: "Strangers, friends, and lovers show specific physiological synchronies in different emotional ...
Gabrieli, Giulio   +2 more
core   +1 more source

Elastic Load Balancing Using Self-Adaptive Replication Management

open access: yesIEEE Access, 2017
Load balancing is a critical problem within storage clusters. Existing algorithms often require high communication overhead, because they have to collect sufficient information that they can then use to dispatch requests for hotspot data fairly.
Jui-Pin Yang
doaj   +1 more source

Mergeable replicated data types

open access: yesProceedings of the ACM on Programming Languages, 2019
Programming geo-replicated distributed systems is challenging given the complexity of reasoning about different evolving states on different replicas. Existing approaches to this problem impose significant burden on application developers to consider the effect of how operations performed on one replica are witnessed and applied on others. To alleviate
Gowtham Kaki   +3 more
openaire   +1 more source

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