Results 101 to 110 of about 2,154,085 (300)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Explaining Health Reform: Uses of Express Lane Strategies to Promote Participation in Coverage [PDF]

open access: yes, 2011
Outlines how, under the 2010 healthcare reform, states could share eligibility data with public assistance programs and federal agencies to expedite enrollment and retention in public coverage, a practice currently applicable only to ...

core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

SURVEILLANCE AND DATA RETENTION IN POLAND [PDF]

open access: yesPublic Policy and Ecnomic Development, 2014
The object of analysis in the present text is the issue of operational control and data retention in Poland. The analysis of this issue follows from a critical stance taken by NGOs and state institutions on the scope of operational control wielded by the Polish police and special services – it concerns, in particular, the employment of “itemized phone ...
openaire   +2 more sources

The Effect of High School Accounting on the Selection of College Major, Performance, Satisfaction, and Retention [PDF]

open access: yes, 2017
The objective of this study is to examine the impact completion of a high school accounting course has on the selection of college major, academic performance in introductory accounting courses, satisfaction with one’s major, and retention.
Marinaccio, Gregory T
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Data Retention

open access: yes
The recent judgements of the CJEU on data retention should not be regarded as an authoritarian move towards a less fundamental rights-sensible position of the Court. Rather, the case law adapts the ever more complex development of the constitutional security law, which was originally dominated by the Member States.
openaire   +2 more sources

Examining first year students' preparedness for studying engineering [PDF]

open access: yes, 2012
The purpose of this paper is to report on initial descriptive data of this longitudinal project which will examine the knowledge, motivation, personality, and learning approaches of first year engineering students and how well they each predict ...
Burton, Lorelle   +4 more
core  

Controlling suction by vapour equilibrium technique at different temperatures, application to the determination of the water retention properties of MX80 clay

open access: yes, 2007
Problems related to unsaturated soils are frequently encountered in geotechnical or environmental engineering works. In most cases, for the purpose of simplicity, the problems are studied by considering the suction effects on volume change or shear ...
Anh-Minh Tang   +15 more
core   +1 more source

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