Results 51 to 60 of about 728,120 (296)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Red flags in data: Learning from failed data reuse experiences [PDF]

open access: yes, 2016
This study examined the data reusers' failed or unsuccessful experience to understand what constituted reusers' failure. Learning from failed experiences is necessary to understand why the failure occurred and to prevent the failure or convert the ...
Yoon, Ayoung
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Dataset Finder: A Tool Utilizing Data Management Plans as a Key to Data Discoverability

open access: yesData Science Journal
In the past years, there has been an increased interest in sharing and reusing research data. While the importance of sharing data is urgent for enabling collaboration, many research projects are currently struggling with setting up a strategy and the ...
Soo-Yon Kim   +4 more
doaj   +1 more source

Reconfigurable VLSI Architecture for Real-Time 2D-to-3D Conversion

open access: yesIEEE Access, 2017
2-D-to-3-D conversion is one way to make full use of 2-D contents to produce 3-D contents. Real-time 2-D-to-3-D conversion is required for 3-D consumer electronic devices, which demands fast processing speed especially for high-definition videos. In this
Weizhi Xu   +6 more
doaj   +1 more source

Improving Opportunities for New Value of Open Data: Assessing and Certifying Research Data Repositories

open access: yesData Science Journal, 2021
Investments in research that produce scientific and scholarly data can be leveraged by enabling the resulting research data products and services to be used by broader communities and for new purposes, extending reuse beyond the initial users and ...
Robert R. Downs
doaj   +1 more source

Hazard and risk assessment for indirect potable reuse schemes: An approach for use in developing Water Safety Plans [PDF]

open access: yes, 2010
This is the post-print version of the final paper published in Water Research. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and ...
Angelina Dominguez-Chicas   +27 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

High-Performance Motion Estimation for Image Sensors with Video Compression

open access: yesSensors, 2015
It is important to reduce the time cost of video compression for image sensors in video sensor network. Motion estimation (ME) is the most time-consuming part in video compression.
Weizhi Xu   +4 more
doaj   +1 more source

SEAD: Preserving Data for Environmental Sciences in Areas of Climate, Land-Use, and Environmental Management [PDF]

open access: yes, 2013
NSF Funded DataNet Project #OCI0940824 • SEAD goal is to contribute infrastructure to the NSF DataNet Vision that supports data • Access • Sharing • Reuse • Preservation • Direct work with data at the NSF STC NCED (National Center for Earth-
et al, et al   +4 more
core  

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