Results 71 to 80 of about 728,120 (296)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Envisioning a data reuse registry

Nature Precedings, 2008
AbstractRepurposing research data holds many benefits for the advancement of biomedicine, yet is very difficult to measure and evaluate. We propose a data reuse registry to maintain links between primary research datasets and studies that reuse this data.
Heather Piwowar, Wendy Chapman
openaire   +2 more sources

The Maritime Record in Scotland from Recording to Presentation

Internet Archaeology
With approximately 18,743 km of coastline along the high-water line, 462,315 km² of sea and over 900 islands, Scotland has a rich and diverse marine heritage. The maritime record for Scotland forms part of the National Record of the Historic Environment (
Peter McKeague
doaj   +1 more source

Social science research data curation

Libellarium: Journal for the Research of Writing, Books, and Cultural Heritage Institutions, 2017
Data curation is attracting a growing interest in the library and information science community. The main purpose of data curation is to support data reuse.
Guangyuan Sun, Christopher S.G Khoo
doaj   +1 more source

Distributed memory compiler methods for irregular problems: Data copy reuse and runtime partitioning [PDF]

, 1991
Outlined here are two methods which we believe will play an important role in any distributed memory compiler able to handle sparse and unstructured problems. We describe how to link runtime partitioners to distributed memory compilers.
Das, Raja, Mavriplis, Dimitri, Ponnusamy, Ravi, Saltz, Joel   +3 more
core   +2 more sources

Data Reuse: comparing the principles

, 2022
Government and commercial organisations have accrued vast amounts of data over years of investment. This data is worth billions of pounds but is not being reused. The ability to reuse data could deliver better value from the initial investment that has been made by allowing an organisation to use their resources more efficiently potentially saving time
Wood, Zena, Hart, Glen
openaire   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Lessons learned from the development of a national registry on dementia care and support based on linked national health and administrative data

Learning Health Systems
Introduction This paper provides insight into the development of the Dutch Dementia Care and Support Registry and the lessons that can be learned from it.
Iris van derHeide, Anneke L. Francke, Carola Döpp, Marianne Heins, Hein P. J. vanHout, Robert A. Verheij, Karlijn J. Joling   +6 more
doaj   +1 more source

Cross-border eServices for public administration driven by Once-Only Principle

Revista Română de Informatică și Automatică, 2020
Nowadays implementing cross-border electronic public services is a top priority for public administrations across EU for accelerating economic development.
Carmen-Elena CÎRNU, Carmen-Ionela ROTUNĂ   +1 more
doaj   +1 more source

Active Transfer Learning with Zero-Shot Priors: Reusing Past Datasets for Future Tasks [PDF]

, 2015
How can we reuse existing knowledge, in the form of available datasets, when solving a new and apparently unrelated target task from a set of unlabeled data?
Gavves, Efstratios, Mensink, Thomas, Snoek, Cees G. M., Tommasi, Tatiana, Tuytelaars, Tinne   +4 more
core   +5 more sources