Results 171 to 180 of about 8,919,237 (294)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Science needs data

Wirtschaftsdienst, 2020
Regina T. Riphahn
doaj   +1 more source

A fact database for toxicological data at the National Institute of Hygienic Sciences, Japan [PDF]

, 1991
Makoto Hayashi, Masahiro Nakadate, Takaharu OSADA, Tamotsu Ishibe, Satoru Tanaka, Akihiko Maekawa, Toshio Sofuni, Yasuko Nakata, Naoko Kanoh, Shigeko HASHIBA, Yusuke Takenaka, Motoi Ishidate   +11 more
openalex   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

High School Data Science Review: Why Data Science Education Should Be Reformed

Harvard Data Science Review, 2021
Angelina Chen
doaj   +1 more source

Preserving the Whole: A Two-Track Approach to Rescuing Social Science Data and Metadata [PDF]

, 1999
Ann Green, JoAnn Dionne, Martin Dennis
openalex   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Cultures and Value of Data Science, Data Science Education, Cybersecurity, and More!

Harvard Data Science Review, 2023
Francesca Dominici
doaj   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

International decade of ocean exploration : progress report, volume 4 : April 1974 to April 1975 / prepared by the U.S. Environmental Data Service, under contract to the National Science Foundation, Office for the International Decade of Ocean Exploration.

, 1975

openalex   +2 more sources