Results 171 to 180 of about 13,470,212 (338)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Exploring barriers and solutions in advancing cross-centre population data science
, 2019 Kerina Jones +3 more
openalex +2 more sources
The Value of Information: A Background Paper on Measuring the Contribution of Space-Derived Earth Science Data to National Resource Management [PDF]
, 2005 Molly K. Macauley
openalex +1 more source
Growing Diversity in Data Science: Shared Lessons from Clinical Trials [PDF]
, 2019 Simari, Robert D.
core +2 more sources
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Recovering the History of Informed Consent for Data Science and Internet Industry Research Ethics
, 2016 Elaine Sedenberg, Anna Lauren Hoffmann
openalex +1 more source
Lessons learned to improve the UX practices in agile projects involving data science and process automation [PDF]
, 2022 Bruna Ferreira +4 more
openalex +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source