Results 211 to 220 of about 12,937,092 (315)

Eleven quick tips to unlock the power of in vivo data science. [PDF]

PLoS Comput Biol
Kieran TJ, Maines TR, Belser JA.
europepmc   +1 more source

Extensions to the Joshua GDMS to support environmental science and analysis data handling requirements

, 1977
J. E. Suich, H. C. Honeck
openalex   +1 more source

“Uneasy science”—the pooling of heterogeneous data [PDF]

, 2002
Eurof Walters
openalex   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Ethical governance for genomic data science in the cloud. [PDF]

Nat Rev Genet
Rahimzadeh V, Nelson SC, Thorogood A, Lawson J, Fullerton SM.   +4 more
europepmc   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Leading Edge of Earth Science Technology. An Introduction of the Comprehensive Earth Science Data Base, GeoRef.

, 2000
Masahiro Ichiki, Riko Modeki, Yasuyuki Nakamura, Mikiko SHIBAO   +3 more
openalex   +2 more sources

“Uneasy science”—the pooling of heterogeneous data: Reply of the authors (#4): [PDF]

, 2002
Jean‐Noël Hugues, David W. Warne
openalex   +1 more source

The Science of Data Science

The Science of Data Science
This report summarizes two talks that I gave at the Advanced Future Studies at Kyoto University in February of 2016. One talk was for the Global Partnership on Science Education through Engagement. In this talk I focused on an emerging educational trend in the United States—the rise of Data Science at both the undergraduate and graduate level—and the ...
openaire  

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source