Results 231 to 240 of about 28,192,111 (316)

Supervised and Unsupervised Learning for Data Science

Unsupervised and Semi-Supervised Learning, 2020

semanticscholar   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Reconstructing decision-making dynamics during public health crises by applying data science to public records. [PDF]

J Public Health Policy
Nadel P, Smith KM.
europepmc   +1 more source

The Social Science Electronic Data Library: Serving the Needs of Data Librarians and Users

, 2001
Michael Jabara Carley, Josefina J. Card
openalex   +2 more sources

Science data collection with polarimetric SAR [PDF]

, 2002
Jørgen Dall, K. Woelders, S.N. Madsen
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

A collaborative approach to advancing research and training in Public Health Data Science-challenges, opportunities, and lessons learnt. [PDF]

Front Public Health
Abade E, Mulugeta W, Orowe I, Hailemariam G, Weke P, Bekele R, Zaugg I, Goldsmith J, Sanchez T, Berhane K.   +9 more
europepmc   +1 more source

Distinct Cytochrome P450 Aromatase Isoforms in Zebrafish (Danio rerio) Brain and Ovary Are Differentially Programmed and Estrogen Regulated during Early Development**This research was supported by grants from the National Science Foundation (IBN-96-05053) and the NIH (P42 ES-07381). The nucleotide sequences reported in this paper have been submitted to the GenBank/EMBL Data Bank with accession numbers AF226619 and AF226620.

, 2001
Mitsuyo Kishida, Gloria V. Callard
openalex   +1 more source

Sharing Publication-Related Data and Materials: Responsibilities of Authorship in the Life Sciences [PDF]

, 2003
Thomas R. Cech, Sean R. Eddy, David Eisenberg, Karen Hersey, Steven H. Holtzman, George Poste, Natasha V. Raikhel, Richard H. Scheller, David B Singer, Mary Waltham   +9 more
openalex   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source