Results 281 to 290 of about 8,919,237 (294)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Understanding the Data in K-12 Data Science

open access: yesHarvard Data Science Review
Rotem Israel-Fishelson   +3 more
doaj   +1 more source

Democratizing data science through data science training

Biocomputing 2018, 2017
The biomedical sciences have experienced an explosion of data which promises to overwhelm many current practitioners. Without easy access to data science training resources, biomedical researchers may find themselves unable to wrangle their own datasets.
Avnish Bhattrai   +13 more
openaire   +3 more sources

The science of managing data science

Communications of the ACM, 2015
Lessons learned managing a data science research team.
openaire   +2 more sources

Introduction to Data Science

2017
You have, no doubt, already experienced data science in several forms. When you are looking for information on the web by using a search engine or asking your mobile phone for directions, you are interacting with data science products. Data science has been behind resolving some of our most common daily tasks for several years.
Laura Igual, Santi Seguí
openaire   +2 more sources

What is Data Science - Introduction to Data Science

2020
Data Science is the technology that goes behind handling and working with data in the 21st century. Data Science concepts have proved to be the pinnacle in the last couple of years with the onset of Artificial Intelligence and Deep..Read More...
openaire   +2 more sources

Data Science

2018
International ...
Amini, Massih-Reza   +8 more
openaire   +3 more sources

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