Results 31 to 40 of about 12,291,752 (225)

Open Data in Science

open access: yesSerials Review, 2008
AbstractOpen Data (OD) is an emerging term in the process of defining how scientific data may be published and re-used without price or permission barriers. Scientists generally see published data as belonging to the scientific community, but many publishers claim copyright over data and will not allow its re-use without permission.
openaire   +5 more sources

Data Science [PDF]

open access: yesThe Computer Journal, 2016
The field of Data Science concerns techniques for extracting knowledge from diverse data, with a particular focus on ‘big’ data exhibiting ‘V’ attributes such as volume, velocity, variety, value and veracity. The field of data science is becoming increasingly influential in the public, private and voluntary sectors, with its overarching aim of ...
Maneth, Sebastian   +1 more
openaire   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

The medical science DMZ: a network design pattern for data-intensive medical science [PDF]

open access: yes, 2017
: Objective We describe a detailed solution for maintaining high-capacity, data-intensive network flows (eg, 10, 40, 100 Gbps+) in a scientific, medical context while still adhering to security and privacy laws and regulations. Materials and Methods
Balas, Edward   +8 more
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Data Science and Ebola [PDF]

open access: yes, 2015
Data Science---Today, everybody and everything produces data. People produce large amounts of data in social networks and in commercial transactions. Medical, corporate, and government databases continue to grow.
Plaat, Aske
core   +2 more sources

Creep curve measurement to support wear and adhesion modelling, using a continuously variable creep twin disc machine [PDF]

open access: yes, 2013
Predictive modelling of wear and adhesion at rolling-sliding contacts such as a railway rail and wheel depends on understanding the relationship between slip and shear force at the contact surface, i.e. the creep verses force curve.
Amsler   +13 more
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

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