Results 61 to 70 of about 13,470,212 (338)
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Perspectives on Marine Data Science as a Blueprint for Emerging Data Science Disciplines
Frontiers in Marine Science, 2021 Earth System Sciences have been generating increasingly larger amounts of heterogeneous data in recent years. We identify the need to combine Earth System Sciences with Data Sciences, and give our perspective on how this could be accomplished within the ...
Maria-Theresia Verwega +14 more
doaj +1 more source
Indonesia embraces the Data Science [PDF]
, 2015 The information era is the time when information is not only largely generated, but also vastly processed in order to extract and generated more information. The complex nature of modern living is represented by the various kind of data.
Situngkir, Hokky
core +2 more sources
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The role of data science in environmental digital twins: In praise of the arrows [PDF]
, 2023 Gordon S. Blair, Peter A. Henrys
openalex +1 more source
LISA Science Results in the Presence of Data Disturbances
, 2004 Each spacecraft in the Laser Interferometer Space Antenna houses a proof mass which follows a geodesic through spacetime. Disturbances which change the proof mass position, momentum, and/or acceleration will appear in the LISA data stream as additive ...
+5 more
core +2 more sources
Data Ethics and Data Science: An Uneasy Marriage?
SSRN Electronic Journal, 2021 Civil society around the world has called for data-driven companies to take their responsibility seriously and to work on becoming more fair, transparent, accountable and trustworthy, to name just a few of the goals that have been set. Data ethics has been put forward as a promising strategy to make this happen.
Keymolen, Esther, Taylor, Linnet
openaire +2 more sources
CCT4 promotes tunneling nanotube formation
FEBS Letters, EarlyView.Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
Data Science in 2020: Computing, Curricula, and Challenges for the Next 10 Years
Journal of Statistics and Data Science Education, 2021 In the past 10 years, new data science courses and programs have proliferated at the collegiate level. As faculty and administrators enter the race to provide data science training and attract new students, the road map for teaching data science remains ...
Aimee Schwab-McCoy +2 more
doaj +1 more source