Results 91 to 100 of about 32,417,955 (343)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Independent living program evaluation for Rebuilding All Goals Efficiently

, 2011
This paper evaluates the outcome of independent living (IL) services provided to clients with Spinal Cord Injuries (SCI) by a local non-profit organization, Rebuilding All Goals Efficiently (RAGE).
Armour, Patricia, Moulton, Debra, Pruett, Araceli   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Excel for data visualization in academic health sciences libraries: a qualitative case study

Journal of the Medical Library Association, 2020
Background: Data visualization is a growing topic of discussion and area of educational programming in health sciences libraries. This paper synthesizes information on eight institutions’ experiences in offering Excel-focused data visualization workshops
Fred Willie Zametkin LaPolla
doaj   +1 more source

Next-Generation EU DataGrid Data Management Services

, 2003
We describe the architecture and initial implementation of the next-generation of Grid Data Management Middleware in the EU DataGrid (EDG) project. The new architecture stems out of our experience and the users requirements gathered during the two ...
Akos Frohner, David Cameron, Diana Bosio, Domenici A, Erwin Laure, Federico Dicarlo, Floriano Zini, Gavin Mccance, Gianluca Volpato, Heinz Stockinger, Joni Hahkala, Kurt Stockinger, Leanne Guy, Levi Lucio, Livio Salconi, Mika Sil, Niklas Karlsson, Olle Mulmo, Paul Millar, Peter Kunszt, Ruben Carvajal-Schiaffino, Sophie Lemaitre, Ville Nenonen, William Bell   +23 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Stepping up to the moment: collaborating on a data management and sharing workshop series

Journal of the Medical Library Association
Background: Many researchers benefit from training and assistance with their data management practices. The release of the Office of Science and Technology Policy’s Nelson Memo and the National Institutes of Health’s new Data Management and Sharing ...
Sara Samuel, Yulia Sevryugina, Mark MacEachern, Kate Saylor, Rachel Woodbrook   +4 more
doaj   +1 more source

Transparent settlement model between mobile network operator and mobile voice over Internet protocol operator

The Journal of Engineering, 2014
Advances in technology have enabled network-less mobile voice over internet protocol operator (MVoIPO) to offer data services (i.e. voice, text and video) to mobile network operator's (MNO's) subscribers through an application enabled on subscriber's ...
Luzango Pangani Mfupe, Mjumo Mzyece, Anish Mathew Kurien   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Data Management Services for Linfield College [PDF]

, 2011
This document describes the data management services available to researchers at Linfield. For researchers who would like to be able to copy and paste sections from this document for use in their data management plans, please download the version in ...
Linfield College
core   +1 more source