Results 91 to 100 of about 6,671,811 (296)
Frustrations and roadblocks in data reference librarianship
IASSIST Quarterly, 2019 As data skills are incorporated into academic curriculum and data becomes more widely available and used in everyday life, many librarians find themselves serving as 'accidental' data librarians in their subject areas. Due to this evolving landscape and
Alicia Kubas, Jenny McBurney
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Good Omens: New Services, Accurate Research Data
Journal of eScience LibrarianshipResearch data management and data curation need strong relationships with colleagues, collaborators, and researchers. Because change comes fast, assessment of current services and practices are important so that new paths and initiatives can be developed.
Regina Raboin
doaj +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Developing a Centralized Hub for Research Data Services: Trainings and Resources in Health Sciences Contexts. [PDF]
J Escience Librariansh, 2023 Williamson PO.
europepmc +1 more source
Secure Data Deduplication in Cloud Storage Services [PDF]
Cloudová úložiště se poslední dobou stala výhodnou alternativou k jiným typům úložišť, jejich provozovatelé se však potýkají s problémem jak skloubit optimalizaci a ochranu uložených dat. Pro zajištění utajenosti svých dat by klienti úložiště preferovali
Staněk Jan
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FLICK: developing and running application-specific network services [PDF]
, 2016 Data centre networks are increasingly programmable, with application-specific network services proliferating, from custom load-balancers to middleboxes providing caching and aggregation.
Alim, A +16 more
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Composing Distributed Data-intensive Web Services Using a Flexible Memetic Algorithm
, 2019 Web Service Composition (WSC) is a particularly promising application of Web services, where multiple individual services with specific functionalities are composed to accomplish a more complex task, which must fulfil functional requirements and optimise
Chen, Gang, Ma, Hui, Sadeghiram, Soheila
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Retracted: Discuss the Application of Data Services in Data Health Management of High-Risk Pregnant and Lying-In Women in Smart Medical Care. [PDF]
Scanning, 2023 Scanning.
europepmc +1 more source