Results 151 to 160 of about 23,296,124 (362)
Self-organizing data sharing communities with SAGRES [PDF]
, 2000 Zachary G. Ives, Alon Y. Levy, Jayant Madhavan, Rachel Pottinger, Stefan Saroiu, Igor Tatarinov, Shiori Betzler, Qiong Chen, Ewa Jaslikowska, Su Jing, Wai Tak Theodora Yeung +10 moreopenalex +1 more sourceGA4GH: International policies and standards for data sharing across genomic research and healthcare
Cell Genomics, 2021 H. Rehm, A. Page, Lindsay Smith, Jeremy B. Adams, G. Alterovitz, L. Babb, Maxmillian P. Barkley, M. Baudis, M. Beauvais, Tim Beck, J. Beckmann, S. Beltrán, David Bernick, A. Bernier, J. Bonfield, Tiffany F. Boughtwood, G. Bourque, Sarion R. Bowers, A. Brookes, M. Brudno, Matthew H. Brush, David Bujold, Tony Burdett, Orion J. Buske, M. Cabili, Daniel L. Cameron, R. Carroll, Esmeralda Casas-Silva, D. Chakravarty, B. Chaudhari, S. Chen, J. Cherry, Ju-Hee Chung, M. Cline, Hayley Clissold, R. Cook-Deegan, Mélanie Courtot, F. Cunningham, Miroslav Cupák, Robert M. Davies, Danielle Denisko, M. Doerr, L. Dolman, E. Dove, L. Dursi, S. Dyke, James A. Eddy, K. Eilbeck, K. Ellrott, S. Fairley, Khalid A. Fakhro, H. Firth, Michael S. Fitzsimons, M. Fiume, P. Flicek, I. Fore, M. Freeberg, R. Freimuth, Lauren A. Fromont, J. Fuerth, C. Gaff, Weiniu Gan, Elena M. Ghanaim, David Glazer, R. C. Green, M. Griffith, O. Griffith, R. Grossman, T. Groza, Jaime M Guidry Auvil, R. Guigó, Dipayan Gupta, M. Haendel, A. Hamosh, David P. Hansen, Reece K. Hart, D. Hartley, D. Haussler, Rachele M. Hendricks-Sturrup, C. Ho, Ashley E. Hobb, M. M. Hoffman, Oliver Hofmann, P. Holub, J. Hsu, Jean-Pierre Hubaux, Sarah E. Hunt, Ammar Husami, Julius O. B. Jacobsen, S. Jamuar, Elizabeth L. Janes, Francis Jeanson, A. Jene, A. Johns, Y. Joly, S. Jones, A. Kanitz, Kazuto Kato, Thomas M. Keane, Kristina Kekesi-Lafrance, J. Kelleher, G. Kerry, Seik-Soon Khor, B. Knoppers, Melissa A. Konopko, K. Kosaki, M. Kuba, Jonathan L D Lawson, R. Leinonen, Stephanie Li, Michael F. Lin, Mikael Linden, Xianglin Liu, I. Liyanage, Javier López, A. Lucassen, M. Lukowski, Alice L. Mann, J. Marshall, M. Mattioni, Alejandro Metke-Jimenez, A. Middleton, R. Milne, Fruzsina Molnár-Gábor, Nicola Mulder, M. Munoz-Torres, Rishi Nag, H. Nakagawa, J. Nasir, A. Navarro, T. Nelson, Ania Niewielska, A. Nisselle, Jeffrey Niu, T. Nyrönen, Brian D. O'Connor, Sabine Oesterle, S. Ogishima, Vivian Ota Wang, L. Paglione, Emilio Palumbo, H. Parkinson, A. Philippakis, A. Pizarro, A. Prlić, Jordi Rambla, A. Rendon, Renee A Rider, Peter N. Robinson, K. Rodarmer, L. Rodriguez, Alan F. Rubin, M. Rueda, Gregory A. Rushton, Rosalyn S. Ryan, Gary I. Saunders, Helen Schuilenburg, T. Schwede, S. Scollen, Alexander Senf, Nathan C. Sheffield, Neerjah Skantharajah, A. Smith, Heidi Sofia, Dylan Spalding, A. Spurdle, Zornitza Stark, Lincoln Stein, M. Suematsu, Patrick Tan, J. Tedds, Alastair A. Thomson, A. Thorogood, Timothy L. Tickle, K. Tokunaga, Juha Törnroos, D. Torrents, S. Upchurch, A. Valencia, R. Guimera, J. Vamathevan, Susheel Varma, D. Vears, Coby Viner, Craig Voisin, A. Wagner, S. Wallace, B. Walsh, Marc S. Williams, E. Winkler, B. Wold, Grant M. Wood, J. Woolley, Chisato Yamasaki, Andrew D. Yates, C. Yung, Lyndon J. Zass, K. Zaytseva, Junjun Zhang, P. Goodhand, K. North, E. Birney +201 moresemanticscholar +1 more sourceEscape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk +11 morewiley +1 more sourceShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones +11 morewiley +1 more sourceTargeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker +19 morewiley +1 more source