Results 61 to 70 of about 956,345 (261)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Homeostasis imbalance process ontology: a study on COVID-19 infectious processes

BMC Medical Informatics and Decision Making
Background One significant challenge in addressing the coronavirus disease 2019 (COVID-19) pandemic is to grasp a comprehensive picture of its infectious mechanisms.
Yuki Yamagata, Tatsuya Kushida, Shuichi Onami, Hiroshi Masuya   +3 more
doaj   +1 more source

Optimal Design of Plant Canopy Based on Light Interception: A Case Study With Loquat

Frontiers in Plant Science, 2019
Canopy architecture determines the light distribution and light interception in the canopy. Reasonable shaping and pruning can optimize tree structure; maximize the utilization of land, space and light energy; and lay the foundation for achieving early ...
Liyu Tang, Liyu Tang, Dan Yin, Dan Yin, Chongcheng Chen, Chongcheng Chen, Dayu Yu, Dayu Yu, Wei Han, Wei Han   +9 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

National-scale 10-m maps of cropland use intensity in China during 2018–2023

Scientific Data
The amount of actively cultivated land in China is increasingly threatened by rapid urbanization and rural population aging. Quantifying the extent and changes of active cropland and cropping intensity is crucial to global food security.
Bingwen Qiu, Baoli Liu, Zhenghong Tang, Jinwei Dong, Weiming Xu, Juanzhu Liang, Nan Chen, Jiangping Chen, Laigang Wang, Chengming Zhang, Zhengrong Li, Fangzheng Wu   +11 more
doaj   +1 more source

SI-Mamba: High-Resolution Sea Ice Recognition via RB-NDI Guided State-Space Model

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Sea ice recognition is of great significance for reflecting climate change and ensuring ship navigation safety. In recent years, many deep learning-based methods have been proposed and applied to the segmentation and recognition of sea ice regions ...
Wenjun Hong, Zhanchao Huang, Yongke Yang, Luping You, Junchao Cai, Jiajun Zhou, Weiwang Guan, Hua Su   +7 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

ICA-ASIFT-Based Multi-Temporal Matching of High-Resolution Remote Sensing Urban Images

Cybernetics and Information Technologies, 2016
While SIFT (Scale Invariant Feature Transform) features are used to match High-Resolution (HR) remote sensing urban images captured at different phases with large scale and view variations, feature points are few and the matching accuracy is low ...
Huang Fenghua, Mao Zhengyuan, Shi Wenzao
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source