Results 81 to 90 of about 24,469,419 (259)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Homeostasis imbalance process ontology: a study on COVID-19 infectious processes

open access: yesBMC Medical Informatics and Decision Making
Background One significant challenge in addressing the coronavirus disease 2019 (COVID-19) pandemic is to grasp a comprehensive picture of its infectious mechanisms.
Yuki Yamagata   +3 more
doaj   +1 more source

MSAFNet: Multi-Modal Marine Aquaculture Segmentation via Spatial–Frequency Adaptive Fusion

open access: yesRemote Sensing
Accurate mapping of marine aquaculture areas is critical for environmental management and sustainable development for marine ecosystem protection and sustainable resource utilization.
Guolong Wu, Yimin Lu
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Optimal Design of Plant Canopy Based on Light Interception: A Case Study With Loquat

open access: yesFrontiers in Plant Science, 2019
Canopy architecture determines the light distribution and light interception in the canopy. Reasonable shaping and pruning can optimize tree structure; maximize the utilization of land, space and light energy; and lay the foundation for achieving early ...
Liyu Tang   +9 more
doaj   +1 more source

Data from: Data sharing in sociology journals

open access: yes
Data sharing is key for replication and re-use in empirical research. Scientific journals can play a central role by establishing data policies and providing technologies.
Zenk-M\uf6ltgen, Wolfgang, GESIS - Leibniz Institute for the Social Sciences   +1 more
core   +1 more source

Geospatial data sharing in Saudi Arabia [PDF]

open access: yes, 2003
This research started with a realization that two organizations in Saudi Arabia were spending large amounts of money, millions of dollars in fact, in acquiring separate sets of geospatial data that had identical basemap components. Both the organizations
Lee, Donald C.
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Port of Honolulu Industry and Public Sector Cooperation for Information Sharing / Spring 2010 [PDF]

open access: yes, 2010
(MIST Honolulu)MIST held its third event in Honolulu on November 22-23, 2009. Using a participatory design approach, NPS researchers partnered with federal and commercial stakeholders to hold a workshop to assess the information sharing needs of security
Englehorn, Lyla|Hocevar, Susan   +2 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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