Results 101 to 110 of about 1,181,249 (315)
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingBuilding type information indicates the functional properties of buildings and plays a crucial role in smart city development and urban socioeconomic activities.
Shaofeng Zhang +4 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Sharing healthcare data by manipulating ontological individuals
, 2011 The purpose of this chapter is twofold: 1.We primarily want to disseminate our experiences of using the power of ontological engineering when dealing with interoperability and the problem of data sharing in heterogeneous computational environments in ...
Juric, R., Kataria, P.
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Identifying Data Sharing in Biomedical Literature
, 2008 Many policies and projects now encourage investigators to share their raw research data with other scientists. Unfortunately, it is difficult to measure the effectiveness of these initiatives because data can be shared in such a variety of mechanisms and
Heather Piwowar, Wendy W. Chapman
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
International Journal of Digital EarthLong time series and accurate subsurface temperature data in the global ocean are essential for ocean warming and climate change studies. The sparse in situ observations in the pre-Argo era hinder the reconstruction of long-time series observational data
An Wang, Hua Su
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