Results 91 to 100 of about 128,909 (307)

Active recovery induces greater endurance adaptations when performing sprint interval training [PDF]

, 2019
This study sought to determine effects of recovery intensity on endurance adaptations during sprint interval training (SIT). Fourteen healthy young adults (male: 9 and female: 5) were allocated to 1 of 2 training groups: active recovery group (ARG, male:
Babraj, John, Yamagishi, Takaki
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Low-frequency electrical stimulation combined with a cooling vest improves recovery of elite kayakers following a simulated 1000-m race in a hot environment [PDF]

, 2015
This study compared the effects of a low-frequency electrical stimulation (LFES; Veinoplus® Sport, Ad Rem Technology, Paris, France), a low-frequency electrical stimulation combined with a cooling vest (LFESCR) and an active recovery combined with a ...
Abbiss, Batterham, Bieuzen, Bieuzen, Bishop, Bleakley, Borg, Borges, Cheung, Cortis, Crampton, De Pauw, Duffield, Epstein, Finberg, Gastin, Glaser, Hasegawa, Hausswirth, Hopkins, Hopkins, Jones, Kay, Luomala, Marino, Michael, Minett, Minett, Periard, Ramanathan, Schmidt, Tucker, Vaile, Webster, Wendt, Werner, Yeargin, Zhang   +37 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Kinematic characteristics of barefoot sprinting in habitually shod children [PDF]

, 2018
Background. Anecdotally, a wide variety of benefits of barefoot running have been advocated by numerous individuals. The influence of the alterations in the properties of the shoe on the running movement has been demonstrated in adults at submaximal ...
Keogh, Justin W.L., Koyama, Hiroyuki, Maeda, Kei, Mizushima, Jun, Ohyama-Byun, Keigo, Seki, Keitaro, Shibata, Atsushi   +6 more
core   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Effects of creatine monohydrate supplementation on simulated soccer performance [PDF]

, 2014
Purpose: To determine the effects of acute short-term creatine (Cr) supplementation on physical performance during a 90-min soccer-specific performance test. Methods: A double-blind, placebo-controlled experimental design was adopted during which 16 male
Abt, Grant, Kilding, Andrew E., Williams, Jeremy   +2 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The effectiveness of progressive and traditional coaching strategies to improve iprint and jump performance across varying levels of maturation within a general youth population [PDF]

, 2019
Literature pertaining to youth development has identified the importance of understanding the physical, intellectual and emotional needs of adolescent youth.
Maulder, Peter S, Standing, Regan J
core   +3 more sources

THE INFLUENCE OF AGE AND REACTION TIME ON SPRINT PERFORMANCE: AN ANALYTICAL STUDY ACROSS THE LAST FIVE EDITIONS OF WORLD ATHLETICS CHAMPIONSHIPS

Studia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae
Introduction: Sprinting performance has been shown to depend on multiple physiological variables, among which age and start reaction capacity may exert a major influence. Since hundredths of a second can decide the outcome of sprint races, understanding
Răzvan-Andrei TOMOZEI, Florin HURDUC, Iulian-Marius DUMITRU   +2 more
doaj   +1 more source