Results 101 to 110 of about 128,909 (307)

Correction of the Framingham Risk Score Data Reported in SPRINT [PDF]

open access: yes, 2017
This report describes an error in the Framingham Risk Score data presented in the original SPRINT publication.1 The data, presented in Table 1 of the main SPRINT publication in the New England Journal of Medicine and made available to SPRINT Challenge participants, incorrectly calculated the level of baseline cardiovascular risk of the study ...
Warner, Frederick   +5 more
openaire   +1 more source

BP Reduction, Kidney Function Decline, and Cardiovascular Events in Patients without CKD. [PDF]

open access: yes, 2018
BACKGROUND AND OBJECTIVES: In the Systolic Blood Pressure Intervention Trial (SPRINT), intensive systolic BP treatment (target
Dias, C   +4 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Data base of Acute effect of strength, speed, plyometric, and resisted sprint trainings on sprinting

open access: yes, 2020
Barquero-Jiménez, F. e Salazar-Rojas, W. (2020). Efeito agudo dos treinamentos de força, velocidade, pliometria e velocidade contrarresistência na corrida de velocidade. Pensar en Movimiento: Revista de Ciencias del Ejercicio y la Salud, 18(2),1 - 20.
Barquero Jiménez, José Francisco   +1 more
openaire   +1 more source

UJI VALIDITAS DAN RELIABILITAS INSTRUMEN TES FISIK KURIKULUM DAN PEDOMAN DASAR SEPAKBOLA INDONESIA [PDF]

open access: yes, 2016
Tujuan penelitian ini adalah untuk mengetahui nilai validitas dan reabilitas suatu alat ukur yang digunakan untuk tes fisik sepakbola usia 19 tahun. Metode yang digunakan dalam penelitian ini adalah metode deskriptif.
Nurulhuda, Fauzi Ahmad
core  

The acute effects of heavy sled towing on subsequent sprint acceleration performance [PDF]

open access: yes, 2017
Objectives: The purpose of this study was to assess the practical use of heavy sled towing and its acute implications on subsequent sprint acceleration performance.
Bishop, Chris   +3 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A Scrum-based approach to CMMI maturity level 2 in Web Development environments [PDF]

open access: yes, 2012
Scrum has become one of the most popular agile methodologies, either alone or combined with other agile practices. Besides, CMMI (Capability Maturity Model Integration) is accepted as a suitable model to measure the maturity of the organizations when ...
Escalona Cuaresma, María José   +2 more
core  

Transition from Plan Driven to SAFe : Periodic Team Self-Assessment

open access: yes, 2017
Context: How to adopt, scale and tailor agile methods depends on several factors such as the size of the organization, business goals, operative model, and needs.
Beecham, Sarah   +4 more
core   +1 more source

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