Results 201 to 210 of about 3,580,220 (258)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
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2014 IEEE Geoscience and Remote Sensing Symposium, 2014
EnMAP (Environmental Mapping and Analysis Program; www.enmap.org) is a German, Earth observing, imaging spectroscopy, spaceborne mission planned for launch in 2017. In order to ensure data product standards during the complete mission lifetime operational workflows are established. These cover all activities for pre- and in-flight spectral, radiometric,
Storch, Tobias +9 more
openaire +2 more sources
EnMAP (Environmental Mapping and Analysis Program; www.enmap.org) is a German, Earth observing, imaging spectroscopy, spaceborne mission planned for launch in 2017. In order to ensure data product standards during the complete mission lifetime operational workflows are established. These cover all activities for pre- and in-flight spectral, radiometric,
Storch, Tobias +9 more
openaire +2 more sources
Science, 2002
One of the underlying principles of scientific publication in peer-reviewed journals has been the requirement that the authors make available the data and materials necessary for a reader to reproduce the experiment or analysis and to determine whether the data support the authors' conclusions.
Catherine A, Ball +16 more
openaire +2 more sources
One of the underlying principles of scientific publication in peer-reviewed journals has been the requirement that the authors make available the data and materials necessary for a reader to reproduce the experiment or analysis and to determine whether the data support the authors' conclusions.
Catherine A, Ball +16 more
openaire +2 more sources
Studies in health technology and informatics, 2015
The relationship between data quality and data standards has not been clearly articulated. While some directly state that data standards increase data quality, others claim the opposite. Depending on the type of data standard and the aspects of data quality considered, both arguments may in fact be correct.
Meredith, Nahm, W Ed, Hammond
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The relationship between data quality and data standards has not been clearly articulated. While some directly state that data standards increase data quality, others claim the opposite. Depending on the type of data standard and the aspects of data quality considered, both arguments may in fact be correct.
Meredith, Nahm, W Ed, Hammond
openaire +1 more source
1981
Standards are rules and procedures established by an authority in an attempt to measure the quantity or quality of some object or process. In data processing, standards are promulgated by edp management to measure the quality of data processing systems and their operation.
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Standards are rules and procedures established by an authority in an attempt to measure the quantity or quality of some object or process. In data processing, standards are promulgated by edp management to measure the quality of data processing systems and their operation.
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1992
Abstract Most existing procedures for computer archiving use a ‘fixed format’ file which has a data structure determined by specific data requirements. A fixed format file provides for fast access but the data structure cannot be modified without the need to reformat existing files.
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Abstract Most existing procedures for computer archiving use a ‘fixed format’ file which has a data structure determined by specific data requirements. A fixed format file provides for fast access but the data structure cannot be modified without the need to reformat existing files.
openaire +1 more source
2020
Zur Erfüllung des Once-only-Prinzips zwischen Bürger*innen und Verwaltung ist der reibungslose Austausch von Daten zwischen verschiedenen Behörden auf unterschiedlichen Ebenen unabdingbar. Die Interoperabilität der Daten spielt dabei eine zentrale Rolle.
Döring, Matthias, Noack, Sebastian
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Zur Erfüllung des Once-only-Prinzips zwischen Bürger*innen und Verwaltung ist der reibungslose Austausch von Daten zwischen verschiedenen Behörden auf unterschiedlichen Ebenen unabdingbar. Die Interoperabilität der Daten spielt dabei eine zentrale Rolle.
Döring, Matthias, Noack, Sebastian
openaire +1 more source