Results 91 to 100 of about 42,049,725 (376)

Nine simple ways to make it easier to (re)use your data

open access: yesIdeas in Ecology and Evolution, 2013
Sharing data is increasingly considered to be an important part of the scientific process. Making your data publicly available allows original results to be reproduced and new analyses to be conducted.
Ethan P White   +5 more
doaj  

Structure learning of undirected graphical models for count data [PDF]

open access: yes, 2018
Biological processes underlying the basic functions of a cell involve complex interactions between genes. From a technical point of view, these interactions can be represented through a graph where genes and their connections are, respectively, nodes and
Chiogna, Monica, Nguyen, Thi Kim Hue
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

The UK Biobank resource with deep phenotyping and genomic data

open access: yesNature, 2018
The UK Biobank project is a prospective cohort study with deep genetic and phenotypic data collected on approximately 500,000 individuals from across the United Kingdom, aged between 40 and 69 at recruitment.
Clare Bycroft   +18 more
semanticscholar   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Editing Data Structures [PDF]

open access: yesACM Transactions on Programming Languages and Systems, 1981
Text is not the only data that needs editing. For example, interactive debuggers edit data structures internal to running programs. This paper describes eds, a generalized editor that allows users to edit arbitrary data structures. Examples show eds maintaining simple databases, editing LISP S-expressions, debugging SNOBOL4 programs, and creating and ...
A. A. Lopez, Christopher W. Fraser
openaire   +2 more sources

Algomaster Platform Extension for Improved Usability [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2017
Visualizations of algorithms and data structures can be effectively used for supporting the teaching process. However, such visualization must be comprehensive for students and still semantically correct.
BENEJ Martin, ŠIMOŇÁK Slavomír
doaj  

The Impact of Pair Programming on the Performance of Slow-Paced Students: A Study on Data Structure Courses

open access: yesJournal of Information and Organizational Sciences, 2020
A study shows that pair programming can help slow-paced students in completing Introductory Programming assessment. This paper replicates the study on Data Structure course, in which the completion of the assessments does not only rely on logic but also ...
Mewati Ayub   +3 more
doaj   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data

open access: yesGenetics, 2018
Meisner and Albrechtsen present two methods for inferring population structure and admixture proportions in low depth next-generation sequencing (NGS).
J. Meisner, A. Albrechtsen
semanticscholar   +1 more source

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