Results 101 to 110 of about 3,654,984 (308)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A Novel Shape Classification Approach Based on Branch Length Similarity Entropy

IEEE Access
This study presents a novel feature vector for shape clustering based on the Branch Length Similarity (BLS) entropy profile, which is invariant to translation, rotation, and scaling, enhancing its effectiveness for shape analysis.
Sang-Hee Lee, Cheol-Min Park
doaj   +1 more source

Genome assembly composition of the String "ACGT" array: a review of data structure accuracy and performance challenges. [PDF]

PeerJ Comput Sci, 2023
Magdy Mohamed Abdelaziz Barakat S, Sallehuddin R, Yuhaniz SS, R Khairuddin RF, Mahmood Y.   +4 more
europepmc   +1 more source

A storage and access manager for ill-structured data [PDF]

, 1991
Jeffrey E Kottemann, Michael Gordon, Jack W. Stott   +2 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

A Modular, Logistics-Centric Digital Twin Framework for Construction: From Concept to Prototype

CivilEng
Traditional construction logistics rely on manual processes and fragmented tools, leading to inefficient planning, poor communication, and disorganized supply chains.
Maximilian Gehring, Jascha Brötzmann, Uwe Rüppel   +2 more
doaj   +1 more source

A suggested data structure for transparent and repeatable reporting of bibliographic searching. [PDF]

Campbell Syst Rev, 2022
Haddaway NR, Rethlefsen ML, Davies M, Glanville J, McGowan B, Nyhan K, Young S.   +6 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Community Resource for Innovation in Polymer Technology (CRIPT): A Scalable Polymer Material Data Structure. [PDF]

ACS Cent Sci, 2023
Walsh DJ, Zou W, Schneider L, Mello R, Deagen ME, Mysona J, Lin TS, de Pablo JJ, Jensen KF, Audus DJ, Olsen BD.   +10 more
europepmc   +1 more source

Data-Oblivious Data Structures

, 2014
An algorithm is called data-oblivious if its control flow and memory access pattern do not depend on its input data. Data-oblivious algorithms play a significant role in secure cloud computing, since programs that are run on secret data—as in fully homomorphic encryption or secure multi-party computation—must be data-oblivious.
Mitchell, John C., Zimmerman, Joe
openaire   +2 more sources