Results 131 to 140 of about 11,430,808 (343)
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
The R package for DICOM to brain imaging data structure conversion. [PDF]
Sci Data, 2023 Wulms N +7 more
europepmc +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
A Novel Shape Classification Approach Based on Branch Length Similarity Entropy
IEEE AccessThis study presents a novel feature vector for shape clustering based on the Branch Length Similarity (BLS) entropy profile, which is invariant to translation, rotation, and scaling, enhancing its effectiveness for shape analysis.
Sang-Hee Lee, Cheol-Min Park
doaj +1 more source
Compound data structure for computer aided design; a survey [PDF]
, 1967 J. C. Gray
openalex +1 more source
, 2010 We consider the problem of specifying data structures with complex sharing in a manner that is both declarative and results in provably correct code. In our approach, abstract data types are specified using relational algebra and functional dependencies; a novel fuse operation on relational indexes specifies where the underlying physical data structure
Hawkins, Peter +4 more
openaire +3 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Data Structure for a Time-Based Bandwidth Reservations Problem
, 2003 We discuss a problem of handling resource reservations. The resource can be reserved for some time, it can be freed or it can be queried what is the largest amount of reserved resource during a time interval. We show that the problem has a lower bound of
Brodnik, Andrej, Nilsson, Andreas
core +2 more sources
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Data visualisation approaches for component network meta-analysis: visualising the data structure. [PDF]
BMC Med Res Methodol, 2023 Freeman SC +8 more
europepmc +1 more source