Results 181 to 190 of about 4,856,518 (315)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Issues in adaptive mesh refinement implementation

open access: yesElectronic Journal of Differential Equations, 2007
Physical phenomena often involve discontinuities and/or localized high-gradient areas. The numerical simulation of these problems and conventional techniques (Finite Elements, Finite Volumes, Finite Differences, and Spectral Methods) with a uniform grid ...
Noureddine Hannoun, Vasilios Alexiades
doaj  

Macquarie Island Vegetation and Drainage Structure Data Set

open access: yes
Progress Code: completedStatement: Completeness of coverage: 100%. Completeness of classification: All categories generalised. All categories could be further subdivided.

core  

Designing a resource-efficient data structure for mobile data systems

open access: yes, 2006
Designing data structures for use in mobile devices requires attention on optimising data volumes with associated benefits for data transmission, storage space and battery use. For semi-structured data, tree summarisation techniques can be used to reduce
Gourlay, R.S., Gourlay, Richard Scott
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

DermIDS: Dermatology imaging data structure for scalable and interoperable AI systems. [PDF]

open access: yesProc SPIE Int Soc Opt Eng
Cho C   +9 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy