Results 201 to 210 of about 3,706,151 (258)
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
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SIAM Journal on Computing, 1991
Summary: The purpose of this paper is to analyze the maxima properties (value and position) of some data structures. Our theorems concern the distribution of these random variables. Previously known results usually dealt with the mean and sometimes the variance of the random variables. Many of our results rely on diffusion techniques.
Louchard, Guy +2 more
openaire +1 more source
Summary: The purpose of this paper is to analyze the maxima properties (value and position) of some data structures. Our theorems concern the distribution of these random variables. Previously known results usually dealt with the mean and sometimes the variance of the random variables. Many of our results rely on diffusion techniques.
Louchard, Guy +2 more
openaire +1 more source
1990
We discuss data structures and their methods of analysis. In particular, we treat the unweighted and weighted dictionary problem, self-organizing data structures, persistent data structures, the union-find-split problem, priority queues, the nearest common ancestor problem, the selection and merging problem, and dynamization techniques.
Mehlhorn, Kurt, Tsakalidis, A.
openaire +3 more sources
We discuss data structures and their methods of analysis. In particular, we treat the unweighted and weighted dictionary problem, self-organizing data structures, persistent data structures, the union-find-split problem, priority queues, the nearest common ancestor problem, the selection and merging problem, and dynamization techniques.
Mehlhorn, Kurt, Tsakalidis, A.
openaire +3 more sources
SIAM Journal on Computing, 1988
We consider the problem of answering a series of on-line queries on a static data set. The conventional approach to such problems involves a preprocessing phase which constructs a data-structure with good search behavior. The data structure representing the data set then remains fixed throughout the processing of the queries.
Karp, Richard M. +2 more
openaire +1 more source
We consider the problem of answering a series of on-line queries on a static data set. The conventional approach to such problems involves a preprocessing phase which constructs a data-structure with good search behavior. The data structure representing the data set then remains fixed throughout the processing of the queries.
Karp, Richard M. +2 more
openaire +1 more source