Results 101 to 110 of about 6,963,647 (337)

Data Structures for Halfplane Proximity Queries and Incremental Voronoi Diagrams

, 2017
We consider preprocessing a set $S$ of $n$ points in convex position in the plane into a data structure supporting queries of the following form: given a point $q$ and a directed line $\ell$ in the plane, report the point of $S$ that is farthest from (or,
Aronov, Boris, Bose, Prosenjit, Demaine, Erik D., Gudmundsson, Joachim, Iacono, John, Langerman, Stefan, Smid, Michiel   +6 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Efficient Algorithms for Range Mode Queries in the Big Data Era

Information
The mode is a fundamental descriptive statistic in data analysis, signifying the most frequent element within a dataset. The range mode query (RMQ) problem expands upon this concept by preprocessing an array A containing n natural numbers.
Christos Karras, Leonidas Theodorakopoulos, Aristeidis Karras, George A. Krimpas   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Data Structures for SMEM-Finding in the PBWT. [PDF]

Int Symp String Process Inf Retr, 2023
Bonizzoni P, Boucher C, Cozzi D, Gagie T, Köppl D, Rossi M.   +5 more
europepmc   +1 more source

Experimental data showing the effect of wetting on soil structure transformations: 3D images

, 2022
Dmitriy Ivonin, T. G. Kalnin, A V Dembovetskiy, Е. А. Грачев, Е. В. Шеин   +4 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Motion-BIDS: extending the Brain Imaging Data Structure specification to organize motion data for reproducible research

, 2023
Sein Jeung, Helena Cockx, Stefan Appelhoff, Timotheus Berg, Klaus Gramann, Sören Grothkopp, Elke Warmerdam, Clint Hansen, Robert Oostenveld, bids maintainers, Julius Welzel   +10 more
openalex   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Hierarchical data structures for flowchart. [PDF]

Sci Rep, 2023
Zhang P, Dou W, Liu H.
europepmc   +1 more source