Results 121 to 130 of about 29,004,461 (256)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Blockchain networks: Data structures of Bitcoin, Monero, Zcash, Ethereum, Ripple, and Iota. [PDF]

open access: yesWiley Interdiscip Rev Data Min Knowl Discov, 2022
Akcora CG, Gel YR, Kantarcioglu M.
europepmc   +1 more source

Multiple String Pattern Matching Algorithm Using Multi-Character Inverted Lists

open access: yesAlgorithms
Multiple string matching is a fundamental operation in real-time analytics, cybersecurity, bioinformatics, and large-scale information retrieval. Nevertheless, existing approaches continue to face inherent trade-offs among preprocessing efficiency ...
Chouvalit Khancome
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

AI for Data Quality Auditing: Detecting Mislabeled Work Zone Crashes Using Large Language Models

open access: yes
Ensuring high data quality in traffic crash datasets is critical for effective safety analysis and policymaking. This study presents an AI-assisted framework for auditing crash data integrity by detecting potentially mislabeled records related to ...
Nirmal Acharya   +10 more
core   +1 more source

Data structures based on k-mers for querying large collections of sequencing data sets. [PDF]

open access: yesGenome Res, 2021
Marchet C   +5 more
europepmc   +1 more source

ON SOME ENTERTAINING APPLICATIONS OF THE CONCEPT OF SET IN COMPUTER SCIENCE COURSE

open access: yesÌнформаційні технології в освіті, 2011
Some aspects of programming education are examined in this work. It is emphasised, based on the entertainment value, the most appropriate examples are chosen to demonstrate the different language constructions and data structures.
K. Yordzhev, H. Kostadinova
doaj  

Performance of Linear and Spiral Hashing Algorithms

open access: yesAlgorithms
Linear Hashing is an important algorithm for many key-value stores in main memory. Spiral Storage was invented to overcome the poor fringe behavior of Linear Hashing, but after an influential study by Larson, it seems to have been discarded. Since almost
Arockia David Roy Kulandai   +1 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Political Opportunity Structures - Parties

open access: yes, 2012
Data on the political opportunity structure (POS) in 7 Western European countries (Austria, Belgium, Ireland, Netherlands, Spain, Switzerland, and United Kingdom) between 1990 and 2009.
Joost Berkhout   +9 more
core   +1 more source

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