Results 101 to 110 of about 2,861,627 (269)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Blockchain networks: Data structures of Bitcoin, Monero, Zcash, Ethereum, Ripple, and Iota. [PDF]

open access: yesWiley Interdiscip Rev Data Min Knowl Discov, 2022
Akcora CG, Gel YR, Kantarcioglu M.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Data structures based on k-mers for querying large collections of sequencing data sets. [PDF]

open access: yesGenome Res, 2021
Marchet C   +5 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Related Data for: Scale-Inspired Programmable Robotic Structures with Concurrent Shape Morphing and Stiffness Variation

open access: yes
This is the research data for Scale-Inspired Programmable Robotic Structures with Concurrent Shape Morphing and Stiffness ...
Yang, Xudong   +5 more
core   +1 more source

Standardized Data Structures in Rare Diseases: CDISC User Guides for Duchenne Muscular Dystrophy and Huntington's Disease. [PDF]

open access: yesClin Transl Sci, 2021
Mullin AP   +10 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Visualizing inner structures in multimodal volume data

open access: yes, 2002
With the evolution of medical image acquisition techniques, the capacity and fidelity of image-based diagnosis were extended. The current trend is to acquire information using multiple sources to help medical diagnosis, but the integration of the ...
Musse, Soraia Raupp   +5 more
core   +1 more source

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