Results 121 to 130 of about 6,963,647 (337)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Visualizing Structure and Transitions for Biological Data Exploration [PDF]

, 2017
Kevin R. Moon, David van Dijk, Zheng Wang, Scott Gigante, Daniel B. Burkhardt, William S. Chen, Kristina Yim, Antonia van den Elzen, Matthew J. Hirn, Ronald R. Coifman, Natalia B. Ivanova, Guy Wolf, Smita Krishnaswamy   +12 more
openalex   +1 more source

Development of Novel Data Analysis Techniques for Multi-Point Mapping of Thunderstorm Electrical Structures

, 2022
William Schuster, Garrett Shuldes, Cameron Fischer, Cole Hanson, B. E. Carlson   +4 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

GPU-friendly data structures for real time simulation. [PDF]

Adv Model Simul Eng Sci, 2021
Magnoux V, Ozell B.
europepmc   +1 more source

A Framework for Capturing and Analyzing Unstructured and Semi-Structured Data for a Knowledge Management System

, 2020
Gerald Onwujekwe, Kweku-Muata Osei-Bryson, Nnatubemugo Ngwum   +2 more
openalex   +1 more source

Improve Blockchain Performance using Graph Data Structure and Parallel\n Mining [PDF]

, 2018
Jia Kan, Shangzhe Chen, Xin Huang
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A hybrid approach for the analysis of complex categorical data structures: assessment of latent distance learning perception in higher education. [PDF]

Comput Stat, 2022
Iannario M, D'Enza AI, Romano R.
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source