Results 131 to 140 of about 6,691,397 (341)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

ON SOME ENTERTAINING APPLICATIONS OF THE CONCEPT OF SET IN COMPUTER SCIENCE COURSE

open access: yesÌнформаційні технології в освіті, 2011
Some aspects of programming education are examined in this work. It is emphasised, based on the entertainment value, the most appropriate examples are chosen to demonstrate the different language constructions and data structures.
K. Yordzhev, H. Kostadinova
doaj  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Path Algorithms for Contact Sequence Temporal Graphs

open access: yesAlgorithms
This paper proposes a new time-respecting graph (TRG) representation for contact sequence temporal graphs. Our representation is more memory-efficient than previously proposed representations and has run-time advantages over the ordered sequence of edges
Sanaz Gheibi   +3 more
doaj   +1 more source

Data structures based on k-mers for querying large collections of sequencing data sets. [PDF]

open access: yesGenome Res, 2021
Marchet C   +5 more
europepmc   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Diagnostics of Structural Thinking of Bachelors of Pedagogical Education as a Universal Pedagogical Competence

open access: yesОткрытое образование (Москва)
Structural thinking is an important skill that allows you to identify structures in randomly presented information, see relationships at all levels, makes it possible to break a whole into components and create holistic structures and systems from a set ...
Daria A. Barkhatova   +1 more
doaj   +1 more source

Standardized Data Structures in Rare Diseases: CDISC User Guides for Duchenne Muscular Dystrophy and Huntington's Disease. [PDF]

open access: yesClin Transl Sci, 2021
Mullin AP   +10 more
europepmc   +1 more source

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